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  • Compounded in USA
  • 10k + Members
  • 4.8/5 Rated Excellent

A Strong Start
Begins Today

Be Kinder to yourself. And more effective.

Shop NowGLP-1 Pricing
LegitScript Certified
iSTRYVE Compounded Semaglutide
60-Day Money-Back Guarantee
Licensed Clinicians
4.8/5 Rated Excellent
Compounded in the USA
10,000+ Members Trust iSTRYVE
60-Day Money-Back Guarantee
Licensed Clinicians
4.8/5 Rated Excellent
Compounded in the USA
10,000+ Members Trust iSTRYVE

A weight loss

journey that makes you strive

  • Medications at industry leading prices
  • FSA/HSA approved
GLP-1 Weight Loss
Compounded Semaglutide

GLP-1 WEIGHT LOSS

Lose weight your way.

Learn more about GLP-1 treatments →

Included:

Dietitians
Support groups
Mental health coaching
Woman on iSTRYVE weight loss journey

The average iSTRYVE patient

loses 9 lbs in the first month

32 lbs weight loss

Compounded Tirzepatide

GLP-1/GIP

3k+ sold this month·Free shipping

Compounded TirzepatideGet started

Compounded Semaglutide

GLP-1

1.8k+ sold this month·Free shipping

Compounded SemaglutideGet started

Oral Compounded Semaglutide

GLP-1

1.1k+ sold this month·Free shipping

Oral Compounded SemaglutideGet started

*Medications only issued when clinically appropriate after provider evaluation

How it works

You're never figuring this out alone

Every step is explained by a real person — not left for you to guess.

You tell us where you're starting

A short health questionnaire — no guesswork, no generic plan. Just your goals and history.

A real doctor reviews your case

A licensed provider looks at your answers personally and explains exactly what they recommend and why — before anything ships.

You get exactly what you need

Your dose, supplies, and instructions — built around your plan, not a one-size-fits-all box.

We stay with you the whole way

Ongoing check-ins, dose adjustments, and a care team you can actually reach when you have a question.

Select your starting weight

225 lbs

Your potential weight loss is

34 lbs
Get started

Based on results from actual Istryve® patients

Better health,
one iSTRYVE at a time.

Your custom plan, in less than 5 minutes

01. Take our quiz

Answer a few quick questions to help us understand your goals and medical background.

02. Meet your provider

A clinician reviews your answers and creates a personalized plan for your journey's needs.

03. Begin your journey

Start treatment and get ongoing support, progress tracking and coaching through iSTRYVE.

QUESTIONS

Get the answers you need

Take a short quiz, and a licensed provider personally reviews your answers to confirm eligibility and build a plan around you. If approved, your medication ships with clear instructions — and your care team stays with you for dose adjustments and questions along the way.

GLP-1 medications are typically available to adults with a BMI ≥ 27 with a weight-related condition, or a BMI ≥ 30. A licensed clinician reviews your health profile to confirm whether treatment is appropriate for you.

Plans start well below brand-name pricing, with no insurance required. See full pricing for Semaglutide and Tirzepatide on our GLP-1 Pricing page.

Yes. All iSTRYVE medications are prepared at LegitScript-certified, licensed US pharmacies under pharmacist oversight, using the same active ingredients as FDA-approved GLP-1 medications.

Standard shipping takes 2–5 business days and is free on orders over $100. Orders placed before 12 PM EST ship the same day, with expedited options available at checkout.

We offer a 60-day money-back guarantee. If you're not satisfied, contact us within 60 days of delivery for a full refund — no questions asked.

Your
iSTRYVE feeling
awaits

Start your journey
iSTRYVE feeling awaits